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I am sorry that you have been waiting for a response. I recently just logged onto the site and noted that your question hasn't yet been answered. I am a licensed veterinarian with over 25 years’ experience and would be happy to work with you if you are still needing assistance.
Has she been examined by your vet yet for any of these problems?
Has she ever had a urine sample checked?
Has she ever been tested for heartworm and is she on heartworm preventative medication?
Thanks and I will respond further after you reply. There may be a slight delay while I formulate and type a thorough response or I may be offline, but if so, I will respond as soon as I am able.