I am a neurophysiologist. I have a 12 year old F beagle
with steroid responsive meningitis who has had 4 episodes over the last 6 years.
She generally responds to 20mg prednisione PO within 1h which I taper 25% over 4w.
She had another attack today about noon and was administered 15 mg over 1h and had significant remission, but has been sleeping and awakes every few hours with mild respiratory distress and howls with some pain. She was given another 10mg prednisone PO aboit 1h ago and appears to be resting somewhat restlessly.
As she has had 25mg prednisone over the last 6h I am reluctant to administer a lot more, I have read some papers where dosages up to 40mg/24h would be appropriate for her weight (10kg).
Should I consider administering another 15 mg or more, and if so how much more, over the next 12h?
What symptoms should I watch for?
At what point should I consider he steroid responsive meningitis refractory and consider euthanasia as this condition can cause intractible pain