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Welcome to Justanswer! I am Dr. Altman and happy to assist you both today!I am so sorry for your dog's diagnosis.The dose range for tramadol is 1-4 mg/kg so for a 115 pound dog (52 kg), this would be 50-200 mg every 8 hours. As an extralabel dose it can be used as a 4- 10 mg/kg (500 mg) every 8 hours. I would suggest trying to increase by one tablet to a total of 250 mg every 8 hours to see if that helps with his pain until you can speak to your veterinarian. If no change potentially increasing to 300 mg (an additional 50 mg tablet) an hour later if there is no relief but I would increase by 50 mg increments to see if there is a way to breakthrough his pain and get him comfortable (with a maximum of 500 mg in 8 hours but this will likely cause heavy sedation).I have worked with an oncologist that uses gabapentin (neurontin) and even lyrica for pain management of these types of tumors with success and would definitely discuss this possibility with your veterinarian. He has told me he has good success with this type of medication and can be used in combination with the tramadol.I hope this information helps, I am so sorry you both are having to endure this horrible diagnosis. Please let me know how else I can assist you both today
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