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Thank you for requesting me. I am sorry to hear you are worried about your Great Dane. I am sorry I was not online until now.
I assume you are saying that she is pregnant? Do you know how far along she is, how many days since she was bred? Does she have milk yet? What signs of labor is she showing; is she having contractions?
I have always been told by the reproduction specialists that if there are contractions for 45 minutes without a puppy being born, it is time to see the vet, have her checked. I would have an exam done to see if her cervix is open, and if it is, injections could be tried to get contractions started.
Please let me know how she is doing. Rebecca
How is Lulu doing?