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Ask Dr. Michael Salkin Your Own Question
Dr. Michael Salkin
Dr. Michael Salkin, Veterinarian
Category: Dog Veterinary
Satisfied Customers: 25246
Experience:  University of California at Davis graduate veterinarian with 44 years of experience
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My 6 month old Austrian Shepard ate more than 3 toprimate

Customer Question

Hey. My 6 month old Austrian Shepard ate more than 3 toprimate pills and more than 3 onfi pills while I was at work. I'm not exactly sure how many.
Submitted: 1 year ago.
Category: Dog Veterinary
Customer: replied 1 year ago.
He weighs 25 lbs. he is having various different things, he can't land on his back feet when jumping, is barly walking on his back feet, can get bi polar. Is sleepy.
Customer: replied 1 year ago.
When standing he falls to one side, he is breathing heavily
Customer: replied 1 year ago.
Posted by JustAnswer at customer's request) Hello. I would like to request the following Expert Service(s) from you: Live Phone Call. Let me know if you need more information, or send me the service offer(s) so we can proceed.
Expert:  Dr. Michael Salkin replied 1 year ago.

I regret that I'm not allowed to communicate with customers by phone. Topiramate appears to be well-tolerated in dogs at least up to 4.5 mg/lb - approximately 115 mg for Boss. Single overdoses in dogs caused sedation and ataxia ("drunken sailor") as you're witnessing. Onfi (clobazam) is also well-tolerated; one study suggested an LD50 (the dose at which 50% of dogs die) to be a very high 45 mg/lb or ~1125 mg for Boss. What milligram was the topiramate and clobazam pills, please?

In general, when we don't know how badly intoxicated our dogs are, we admit them to a 24 hour hospital and hasten excretion of the drugs with IV fluids (which promote diuresis/urine production), enemas (which promote excretion through the GI tract), and dose activated charcoal orally in order to adsorb any drug that hadn't been absorbed through the GI tract yet.