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Ask Dr. Michael Salkin Your Own Question
Dr. Michael Salkin
Dr. Michael Salkin, Veterinarian
Category: Dog Veterinary
Satisfied Customers: 24467
Experience:  University of California at Davis graduate veterinarian with 44 years of experience
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MY DOG HAD A BLOOD TEST DONE ,THEY ARE TESTING HIM

Customer Question

MY DOG HAD A BLOOD TEST DONE ,THEY ARE TESTING HIM FOR CUSHING ...HIS TEST
ARE
CATALYST DX
TP 3.9 G/DL LOW ALT 96 U/L NORMAL
ALKP 1667 U/L HIGH
NOW SHE WANTS TO DO A TEST THAT TAKES 8HRS ,WHICH SHE SAID WOULD TELL US IF HE HAS CUSHING ? ARE WE DOING THE CORRECT THING ?
Submitted: 1 year ago.
Category: Dog Veterinary
Expert:  Dr. Michael Salkin replied 1 year ago.
Aloha! You're speaking to Dr. Michael Salkin
If Ozzie has been eating you out of house and home and drinking like a fish, Cushing's needs to be considered. Is this the case, please?
Customer: replied 1 year ago.
yes ,he has and he has put a lot of weight he's 34lbs... this test that the dr.wants to do is a 8hr test ,will this tell us for sure he has cushing ....then what type meds ?
Expert:  Dr. Michael Salkin replied 1 year ago.
Thank you! That's a hunk of doxi...and doxis are over-represented with Cushing's disease. The test of choice is a low-dose dexamethasone suppression test consisting of 3 blood draws and one injection of dexamethasone between the 1st and 2nd blood draw. The test is relatively inexpensive and easy to interpret. It often identifies Cushing's and pituitary-dependent Cushing's at the same time. A pituitary tumor causes Cushing's 85% of the time.
While a very good test, results can be affected by acute stress, excitement, aggression, fear, and concurrent illness. False-positive and false-negative test results can occur. Ozzie's vet will need to clarify if adrenal-dependent Cushing's is present instead - an adrenal gland tumor in this case - and then treat accordingly. The most common pituitary dependent Cushing's is usually treated with trilostane - an oral drug administered twice daily indefinitely. The less common adrenal dependent Cushing's is addressed surgically although medical therapy can be palliative - but not entirely successful.
Please continue our conversation if you wish.