Thanks for the additional information.

I am very sorry to hear that Buster is not feeling well at this time. Based on what you are describing a fever is definitely possible. Watery red eyes can be caused by many different reasons, but here are some of the most common:

- Uveitis which is inflammation on the inside of the eye. This can be caused by an infection in the body.
- Allergies to the environment
- An infection in his eyes such as conjunctivitis


A fever or an infection in his body is a very likely cause as this could cause him to be lethargic and could cause his eyes to be red. Some of the most common infections in dogs are:

- An upper respiratory infection
- A tick borne disease such as Lyme disease, Ehrlichia, or even Rocky Mountain Spotted Fever
- Leptospirosis which is a bacteria that causes kidney and liver disease
- A kidney infection form bacteria
- A liver or gall bladder infection
- Unfortunately cancer could also cause his symptoms
- Eating something toxic could also be a cause

At this point I would definitely consider taking him to a vet. Your vet will need to examine him and most likely check some blood work on him to give you a more definitive diagnosis. If he is eating and drinking some, you do not necessarily have to rush him to a vet but he should be taken to a vet within the next 1-2 days if possible.

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More then likely the best medication would be an antibiotic. Since these are only available by prescription you will not be able to get one tonight unless you can contact your vet if they take calls after hours.

Aspirin is a very safe medication that could be considered to help drop a fever. Since he is not vomiting or having diarrhea then this medication should be safe to give him for one dose tonight. This should help him feel better also. The dose is 5 mg per pound every 12 hours. Other then aspirin I would not give him any other medications without seeing your vet.