Welcome to JustAnswer! I would be happy to assist you. I am a 2003 graduate from UC Davis and a Medical Director of a 4 veterinarian practice.
No, it is not. That vaccine, in particular, is one of the most benign, and most dogs (not to mention a 80 pounder) wouldn't have any pain at all 2 days later.
So, I do not believe any of the symptoms you are observing are related to the vaccine.