I think Atopica is an excellent product. I have no experience with Mycoplex Coriolus, so I can't speak for that. I do feel that in general, many of the issues that you discussed in the previous thread are most likely allergy related and it can be very hard to figure out what those allergies are, and even if you do, then what do you do about them? If you can eliminate the allergen (like food), great, do so. But in the majority of cases, the dog is going to have more than just food allergies and so you are left with suppressing symptoms (which is all we do for people, really!). Steroids and Atopica are your best weapons for symptom relief, and of those two, Atopica is less damaging over time. Keep in mind as well, that ideally, with Atopica, you may have to start with twice a day dosing, but the goal is to taper the dog down to the lowest dose (milligram and schedule wise) that keeps symptoms at bay. For example, I may start a large dog at 100 mg once a day until symptoms are gone. Then I may decrease to every other day, then you can try playing with the dose--you can try going to every 3-4 days or dropping the milligrams. Any time symptoms reappear, you have to go back and try again. So at first, it can be pretty expensive, but if it works well, and you can get Merl down to every third day dosing, for example, the cost gets a little better. (And also keep in mind how much you are saving in antibiotics, repeat visits to the vet for hot spots
meds, etc, if it works.) The same may be true for the natural product, but like I said I don't have experience with it, so I can't say.
So long story short, yes, I think you should definitely try one of those immune-suppressing drugs and see if it helps.