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Dr. Andy
Dr. Andy, Medical Director
Category: Dog Veterinary
Satisfied Customers: 28117
Experience:  UC Davis graduate, emphasis in dermatology, internal medicine, pain management
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What is max dosage of clemastine for dogs (per pound)

Resolved Question:

What is max dosage of clemastine for dogs (per pound)
Submitted: 5 years ago.
Category: Dog Veterinary
Expert:  Dr. Andy replied 5 years ago.
Hello,
You can find very specific dosing directions in the following link:

http://www.petplace.com/drug-library/clemastine-antihist-i-dayhist-tavist/page1.aspx

However, it is true that this antihistamine may not be as effective in dogs.

Another very common over-the-counter alternative is Benadryl.
Benadryl can be given at a dose of 1mg per pound of body weight. Keep in mind, Benadryl tablets and liquids come in different sizes. So, an approximately 25 pound dog can get a full 25mg tablet or a half of a 50mg tablet. I usually avoid the liquid Benadryl in larger dogs (you would have to give too much of it). You can give Benadryl every 8-12 hours.
http://www.petplace.com/drug-library/diphenhydramine-benadryl/page1.aspx

One last thought.
Some antihistamines can get a synergistic effect when used also with essential fatty acid supplements.
Definitely, if you plan to give an antihistamine long-term,    
combine it with an EFA supplement. I prefer the veterinary products dosed for pets.   Your vet
should carry a product on their shelf, or over-the-internet you can look for Aller G3, 3V caps,
EFA-z, or Derm caps.

Hope that info helps
Good Luck
Dr. Andy
Dr. Andy, Medical Director
Category: Dog Veterinary
Satisfied Customers: 28117
Experience: UC Davis graduate, emphasis in dermatology, internal medicine, pain management
Dr. Andy and 2 other Dog Veterinary Specialists are ready to help you
Customer: replied 5 years ago.
Site given for dosage instructions did not help(they said 1/2 to 1 caps per day) I have a 125 pound Giant Schnauzer who has an itching problem on his feet and chin. My vet said he could take 5 each of 1.25mg caps two times a day. I had been giving him 2 each twice a day, on Vets advice, with little success. I think 5 twice a day is a little too much. Thats why I ask--what is the MAX DOSAGE per pound of Clemastine.
Expert:  Dr. Andy replied 5 years ago.
Clemastine is dosed in dogs at 0.025 – 0.05 mg per pound (0.5 – 0.2 mg/kg) PO two times daily

Therefore, at 125 pounds * 0.05 = 6.25mg twice daily.

With 2.68mg tablets:

6.25 / 2.68 = 2.33 tablets

So, round up just a bit and your dose is 2.5 tablets of the 2.68mg tablets.

If you only have the 1.34mg tablets you would give 5 tablets.

Just remember, the studies to date do not favor clemastine. I am not even sure why your vet is recommending it.

Benadryl or a prescription of hydroxyzine would be much preferred. Also, adding that essential fatty acid would be helpful.

If an allergy condition, only about 30% of dogs will even respond to a "good" antihistamine combined with a fish oil.

Hope that info helps
Good Luck
Dr. Andy
Expert:  Dr. Andy replied 5 years ago.
Here's a ton of extra info you may appreciate. I just don't feel you getting that great of direction from your vet. Especially, for feet lickers/chewers, the two highest suspicions would be for food and/or enviornmental allergies:

So, to rule-out food allergies you need to do a diet trial.
Summary: The primary protein in most dog foods is lamb, chicken, or beef. The primary carbohydrate is rice or corn. So, we need to change both. The most popular alternative diets are Venison and Potato, Duck and Potato, or Fish and Potato. It is available in prescription formulas (i.e. Science Diet D/D) or you can find some similar foods at the big pet stores like PetSmart or PetCo. Keep in mind, holistic or all-natural foods are not necessarily any better when trying to remove a food allergy. Chicken is chicken, and rice is rice. When you perform a diet trial, you must stick with the food for 2-3 months to see if there is any benefit. No other treats or human food can be given during this time period.
http://www.petplace.com/dogs/food-allergy-in-dogs/page1.aspx

Also, definitely read about ENVIRONMENTAL ALLERGIES (atopy). Some pets, suffer from both environmental and food allergies:
http://www.petplace.com/dogs/atopy-in-dogs/page1.aspx

If you want to actual diagnose what in the environment may be causing the allergy, you can do an allergy test. Now, you don’t have to shave half the body and do the old grid test on the skin. There is now a rather good blood test that looks for allergies to weeds, trees, grasses!, molds, even house dust mites. You can read more about it here:
http://www.varlallergy.com/index.html

Now, in addition to allergies, there are also some other common causes of skin problems or secondary infections that can occur:
Mites (demodex or scabies). Demodex is not contagious, however, scapies or sarcoptic mange is zoonotic. So, keep in mind, when ever someone mentions mange, it is important to distinguish between which mite. To diagnose if there are mites, your veterinarian can perform an easy skin scraping test in the hospital. It is not always 100% accurate, but a good start. It can be difficult sometimes to scrape out the mites.
Demodex:   http://www.petplace.com/dogs/demodicosis-red-mange-in-dogs/page1.aspx
Scabies:       http://www.petplace.com/dogs/sarcoptic-mange-in-dogs/page1.aspx
Skin scraping: http://www.petplace.com/dogs/skin-scraping/page1.aspx

Secondary yeast or bacterial infections (very common)
Frequently, the skin will be inflamed, have an odor, and/or oily component.
http://www.petplace.com/dogs/skin-discharge-or-odor-in-dogs/page1.aspx


TREATMENT OPTIONS (A small representative list)
Steroids. Veterinarians will either give an injection that can last from hours to weeks, or send home oral steroids like prednisone or dexamethasone.
Antihistamines. A prescription of hydroxyzine is common. Sometimes, over-the-counter Benadryl will help.

Benadryl can be given at a dose of 1mg per pound of body weight. Keep in mind, Benadryl tablets and liquids come in different sizes. So, an approximately 25 pound dog can get a full 25mg tablet or a half of a 50mg tablet. I usually avoid the liquid Benadryl in larger dogs (you would have to give too much of it). You can give Benadryl every 8-12 hours.
http://www.petplace.com/drug-library/diphenhydramine-benadryl/page1.aspx

Essential fatty acid supplements. Definitely, if you plan to give an antihistamine long-term,    
combine it with an EFA supplement. I prefer the veterinary products dosed for pets.   Your vet
should carry a product on their shelf, or over-the-internet you can look for Aller G3, 3V caps,
EFA-z, or Derm caps.
Some vets use a product called Temaril-P. It’s an antihistamine with a low-dose steroid built into
the same tablet.
Atopica. Neat stuff. Can take a few weeks to be of benefit. Not the most cost-effective, but can
be incredible for allergies when the above does not work. Read the link below for more
information.
http://www.us.atopica.com/indexConsumer.shtml
Your vet may also carry some special sprays or shampoos for the skin. Some contain topical
steroids with antibiotics. Others contain analgesics to comfort the skin like “Relief Shampoo” and
“Relief Spray”
Lastly, oral antibiotics or antiyeast medication, if indicated.

Thought you would like the info...

Good Luck

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