How JustAnswer Works:

  • Ask an Expert
    Experts are full of valuable knowledge and are ready to help with any question. Credentials confirmed by a Fortune 500 verification firm.
  • Get a Professional Answer
    Via email, text message, or notification as you wait on our site.
    Ask follow up questions if you need to.
  • 100% Satisfaction Guarantee
    Rate the answer you receive.

Ask Dr. Loretta Your Own Question

Dr. Loretta
Dr. Loretta, Dog Veterinarian
Category: Dog Veterinary
Satisfied Customers: 26159
Experience:  25 years of experience in surgery and internal medicine.
Type Your Dog Veterinary Question Here...
Dr. Loretta is online now
A new question is answered every 9 seconds

My dog has high ALT liver enzymes. He was having seizure and

Customer Question

My dog has high ALT liver enzymes. He was having seizure and was put on phenobarbitol and potassium bromide. His Liver enzymes got worse from 898 to 3000. He is now off the phenobarbitol. a week ago abnormal growths were discovered in one nostral. he is now on prednisone. I have been giving him milk thistle 80% silymarin twice a day for quite some time as well as S-Adenosylmethionine once a day and a mens vitamine once a day.
I have not hand the growth tested for cancer because at 11 1/2 years old I would not put him through radiation and chemo. I bought some supplements, Onco-x with contains many vitamins but also 80% silymarin. my dog weighs 34lbs. how much is too much silymarin can too much do more harm?
Submitted: 5 years ago.
Category: Dog Veterinary
Expert:  Dr. Loretta replied 5 years ago.

Hi Colleen. I am so sorry to hear about your guy. He is having a very difficult time but I am very proud of how you are handling this situation. The addition of Milk thistle and the S-Adenosylmethionine is a very good thing for your guy with such a bad liver disease. The dosage of silymarin is 200 mg per 10pounds so for your guy, 600 mg divided twice daily is a good dose. The rule of thumb is a percentage of the human dose such as 30% for a 30 lb dog such as yours. The container of supplement containing the silymarin will have the mg per dose of this product and you can figure it out from there.

 

From all my reading, there really is no way to overdose on milk thistle. the body will excrete what it does not use.

 

Good Luck with your guy!!!

 

Dr. Loretta
Click REPLY if you need more info.Click ACCEPT if I have answered your question.

Thank you so much for your question! This cannot replace an exam by a veterinarian.
Feedback and Bonuses are encouraged.

 

 

 

 

 

Dr. Loretta, Dog Veterinarian
Category: Dog Veterinary
Satisfied Customers: 26159
Experience: 25 years of experience in surgery and internal medicine.
Dr. Loretta and 8 other Dog Veterinary Specialists are ready to help you
Customer: replied 5 years ago.
Thank you
Expert:  Dr. Loretta replied 5 years ago.
Colleen, you are very welcome!! My thoughts are with you and your old friend!!
Customer: replied 5 years ago.
this is Mikeys 2nd week on the prednison. Ideally he should be on 1 pill every other day at this point. But, when I try to skip a day he sneezes hard get a bloody nose. how hard is it on him to be on prednisone everyday? Are there alternatives?
Expert:  Dr. Loretta replied 5 years ago.

HI again, Colleen. The prednisone is a part of a chemotherapeutic regimen and Mikey needs to have this. If the dose is low(5-10mg), there is no harm. THis is a very low dose(a therapeutic dose is 1 mg per pound), and there are no lther alternatives for the effect that we need, unfortunately. Even if you give 5-10 mg every day, there is no harm to his alreday compromised system. A higher dose will be hard on his liver but, sometimes, you have to compromise for the best quality of life for Mikey.

 

Does that help, Colleen?

Customer: replied 5 years ago.
yes thanks again
Expert:  Dr. Loretta replied 5 years ago.
You are very welcome again, Colleen!!

JustAnswer in the News:

 
 
 
Ask-a-doc Web sites: If you've got a quick question, you can try to get an answer from sites that say they have various specialists on hand to give quick answers... Justanswer.com.
JustAnswer.com...has seen a spike since October in legal questions from readers about layoffs, unemployment and severance.
Web sites like justanswer.com/legal
...leave nothing to chance.
Traffic on JustAnswer rose 14 percent...and had nearly 400,000 page views in 30 days...inquiries related to stress, high blood pressure, drinking and heart pain jumped 33 percent.
Tory Johnson, GMA Workplace Contributor, discusses work-from-home jobs, such as JustAnswer in which verified Experts answer people’s questions.
I will tell you that...the things you have to go through to be an Expert are quite rigorous.
 
 
 

What Customers are Saying:

 
 
 
  • It was so professional, so personally concerned (as we were) and you answered all of our questions. George and I are so happy that I found "JustAnswer" on my Google search -- you are now in my "Favorites" list! And, yes we do love our kitty - she makes our life complete! Bev & George Boca Raton, FL
< Last | Next >
  • It was so professional, so personally concerned (as we were) and you answered all of our questions. George and I are so happy that I found "JustAnswer" on my Google search -- you are now in my "Favorites" list! And, yes we do love our kitty - she makes our life complete! Bev & George Boca Raton, FL
  • Wonderful service, prompt, efficient, and accurate. Couldn't have asked for more. I cannot thank you enough for your help. Mary C. Freshfield, Liverpool, UK
  • This expert is wonderful. They truly know what they are talking about, and they actually care about you. They really helped put my nerves at ease. Thank you so much!!!! Alex Los Angeles, CA
  • Thank you for all your help. It is nice to know that this service is here for people like myself, who need answers fast and are not sure who to consult. GP Hesperia, CA
  • I couldn't be more satisfied! This is the site I will always come to when I need a second opinion. Justin Kernersville, NC
  • Just let me say that this encounter has been entirely professional and most helpful. I liked that I could ask additional questions and get answered in a very short turn around. Esther Woodstock, NY
  • Thank you so much for taking your time and knowledge to support my concerns. Not only did you answer my questions, you even took it a step further with replying with more pertinent information I needed to know. Robin Elkton, Maryland
 
 
 

Meet The Experts:

 
 
 
  • Dr. Debbie

    Dog Veterinarian

    Satisfied Customers:

    902
    Companion animal veterinarian practicing for over 10 years.
< Last | Next >
  • http://ww2.justanswer.com/uploads/DE/debkatreyn/2011-11-28_33650_682e.64x64.jpg Dr. Debbie's Avatar

    Dr. Debbie

    Dog Veterinarian

    Satisfied Customers:

    902
    Companion animal veterinarian practicing for over 10 years.
  • http://ww2.justanswer.com/uploads/VE/vetforyou/2012-6-20_33122_PearlPhoto.64x64.jpg Dr. Andy's Avatar

    Dr. Andy

    Medical Director

    Satisfied Customers:

    13796
    UC Davis graduate, emphasis in dermatology, internal medicine, pain management
  • http://ww2.justanswer.com/uploads/doggfone1/2009-07-16_133633_vet_pic.jpg Dr. Scott's Avatar

    Dr. Scott

    Veterinarian

    Satisfied Customers:

    9550
    12 years of small animal, equine and pocket pet medicine and surgery.
  • http://ww2.justanswer.com/uploads/RY/rydergar/2012-6-6_192240_IMG0328.64x64.JPG Dr. Gary's Avatar

    Dr. Gary

    Dog Veterinarian

    Satisfied Customers:

    7758
    DVM, Emergency Veterinarian, BS (Physiology)
  • http://ww2.justanswer.com/uploads/AN/andrewDVM/2012-4-27_12585_iStock000011751407XSmall.64x64.jpg Dr. Drew's Avatar

    Dr. Drew

    Dog Veterinarian

    Satisfied Customers:

    6598
    Small Animal Medicine and Surgery
  • http://ww2.justanswer.com/uploads/1I/1ISUDVM/2011-3-1_22028_Honeymoon2005075294928803490646858.64x64.jpg Dr. Bruce's Avatar

    Dr. Bruce

    Veterinarian

    Satisfied Customers:

    6377
    13 years of experience as a small animal veterinarian
  • http://ww2.justanswer.com/uploads/BI/bigislandvet/2013-2-21_214244_IMG0357.64x64.JPG Dr. Michael Salkin's Avatar

    Dr. Michael Salkin

    Big Island Vet

    Satisfied Customers:

    6049
    University of California at Davis graduate veterinarian with 41 yrs. of experience.