I am sorry to hear about your multiple medical problems that have required multiple surgeries without relief.
Here is what I understand about Skin and soft tissue infection (SSTI) with M. Abscessus.
1. It is rare, hence definite treatment protocols are not established
2. Antibiotic sensitivity tests are helpful in deciding treatment
3. General treatment involves clearing the local area of all pus and then using the antibiotics
The treatment of serious M. abscessus complex disease usually involves initial combination antimicrobial therapy with a macrolide (clarithromycin 1,000 mg daily or 500 mg twice daily, or azithromycin 250 mg–500 mg daily) plus intravenous agents for at least 2 weeks to several months followed by oral macrolide–based therapy (2). The drugs of choice for initial intravenous administration are amikacin (25 mg/kg 3×/wk) plus cefoxitin (up to 12 g/d given in divided doses) or amikacin (25 mg/kg 3×/wk) plus imipenem (500 mg 2–4×/wk)
In your case, I believe that these antibiotics should help.
The side-effects that you have read are rare, and we have used Amikacin and clarithromycin even in kids with minimal problems.
Early treatment is the best way to get a cure, so do not delay the treatment, as far as possible,
Also try to improve your immunity with better diet, avoidance of processed foods, and natural supplements with zinc to boost your immunity,
Dr. Gupta, MD