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When there is itching without a rash, there are several conditions to consider. It could be a form of eczema or allergic inflammation of the skin. It could be related to excessive dryness of the skin in that area of the itching. And it could be related to irritation of the nerves that serve this skin. Infections also can sometimes cause itching as a sole symptom, although there is usually a rash or other changes in the skin.
From your description, it sounds like your doctor has tried different medicines for these various conditions, but you did not specify which medicines have been tried, so I may repeat some of the previously used medicines. A long-acting oral antihistamine, such as cetirizine or loratidine, would be reasonable. Using a moisturizing cream can help with eczema or excessive dryness. Nerve mediated itching may improve with certain anticonvulsants, such as gabapentin or pregabalin, or certain antidepressants, such as amitriptyline or duloxetine, each of which appear to each the firing of the nerves, although the amitriptyline also has some antihistamine action.
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