Sometimes yes sometimes no depending on what I was sick from. This time I had a sinus infection and my doctor prescribed Levoquin but the rash was there before I had ever taken any antibiotic. I had used Musinex D and Ibuprofen but the rash started before use of those also. I got the same rash back in April when I had a stomach virus and didn't see a doctor. The only thing I took then was imodium. The time before that I had a c-section in January and was on the pain killers and Ibuprofen.