Hi there Scott and welcome
The Joystick is designed for certain games, especially flying games, and within the game you will be selecting the joystick as the controlling device.
The buttons are customizable and you do that via the installed Logitech Profiler.
There is a film that will step you how to do this and you can follow it here
You can also easily profile it for specific games depending on which buttons you need for which game.
Let me know please if this clears it up for you, or if you have anything else you wish to ask me please