here is a service bulletin
Subject: SES Light and P0300 When Towing , Cruising Uphill or on Hard Acceleration - 4.3 5.0 5.7 accelerate cruise cylinderhead RPO L30 L31 L35 LF6 LU3. DTC P0300 P0301 P0302 P0303 P0304 P0305 P0306 P0307 P0308 PIP3081 - (07/23/2004)Models: (96-02 Chevrolet Astro) and (96-02 GMC Safari) and (96-00 Old Body Style Chevrolet Suburban) and (96-00 Old Body Style Chevrolet Tahoe) and (96-02 Chevrolet Express) and (96-00 GMC Yukon) and (96-00 Chevrolet Old Body Style C/K Truck) and (96-00 GMC Old Body Style C/K Truck) and (96-02 GMC Savana) and (96-99 P32 Cab and Chassis) and (96-02 Chevrolet S-10) and (99-02 Chevrolet Silverado with 4.3L V-6 Engines (96-02 GMC Sonoma) and (96-02 GMC Sierra with 4.3L V-6 Engines).The following diagnosis might be helpful if the vehicle exhibits the symptom described.Condition/Concern: The vehicle may exhibit a SES Light due to a P0300 and misfire. If the misfire is related to the information below, it will typically happen while cruising uphill, pulling a trailer or on hard acceleration and then stop misfiring shortly after returning to an idle. Typically, cylinders 3,4,5 or 6 will be the ones to experience this.Recommendation/Instructions: If the P0300 diagnostics did not isolate a concern, the following may help:Remove the valve cover, valve springs and valve seals on the effected cylinder or cylinders. A small wire tie or rubber bands can be placed in the valve stem keeper groove to prevent the valve from falling into the cylinder. Rotate the valve while moving it up and down in the guide to see if it binds. If a binding valve is found, remove both cylinder heads and use either of the following methods to increase the stem to guide clearance:
Reassemble the cylinder heads using new valve seals.Please follow this diagnosis process thoroughly and complete each step. If the condition exhibited is resolved without completing every step, the remaining steps do not need to be performed.NOTE: GM bulletins are intended for use by professional technicians, NOT a "do-it-yourselfer". They are written to inform these technicians of conditions that may occur on some vehicles, or to provide information that could assist in the proper service of a vehicle. Properly trained technicians have the equipment, tools, safety instructions, and know-how to do a job properly and safely. If a condition is described, DO NOT assume that the bulletin applies to your vehicle, or that your vehicle will have that condition. See your GM dealer for information on whether your vehicle may benefit from the information.
any other codes?
has fuel pressure been checked?
CIRCUIT DESCRIPTION The Crankshaft Position (CKP) sensor is the primary input to determine if misfire is occurring. Engine misfire is detected by monitoring crankshaft speed variations between cylinders. If a crankshaft deceleration occurs during a combustion or power stroke, the control module will compare this change in crankshaft speed to the previous cylinder. If the crankshaft speed change is more than a maximum allowable speed, the misfire is detected. Misfire may occur in a specific cylinder or in all cylinders randomly.When an engine is misfiring, brief decelerations in crankshaft rotational speed will be detected by the CKP. The control module determines which cylinder has misfired based upon the Camshaft Position (CMP) sensor input. Misfire data is stored for each cylinder in separate accumulators. After 100 combustion events, the misfire totals are compared to a calibrated maximum number. If the misfire is excessive, this Diagnostic Trouble Code (DTC) will set.CONDITIONS FOR RUNNING THE DTC IMPORTANT: If start-up Engine Coolant Temperature (ECT) is less than -7°C (+20°F) , misfire detection is delayed until the ECT is more than 21°C (70°F) . If the start-up ECT is more than -7°C (+20°F) , misfire detection begins after a 5 second delay.
CONDITIONS FOR SETTING THE DTC The VCM detects a deceleration in the crankshaft speed characteristic of either an emission misfire or a catalyst damaging misfire.ACTION TAKEN WHEN THE DTC SETS If the VCM determines that the engine misfire is significant enough to have a negative impact on emissions, the VCM turns ON the Malfunction Indicator Lamp (MIL) after the misfire has been detected on 2 non-consecutive trips under the same operating conditions. If the misfire is severe enough that catalytic converter damage could result, the MIL flashes while the misfire is present.CONDITIONS FOR CLEARING THE MIL/DTC
An intermittent may be caused by any of the following conditions:
Thoroughly inspect any circuitry that is suspected of causing the intermittent complaint. Refer to Testing for Intermittent and Poor Connections in Diagrams.If a repair is necessary, refer to Wiring Repairs or Connector Repairs in Diagrams.TEST DESCRIPTION The numbers below refer to the Step numbers on the diagnostic table.