Now Smoke's situation does raise some serious concerns. His GI signs (the vomiting, appetite loss, and diarrhea) do of course raise concerns of a viral or bacterial gut infection, pancreatitis, IBD, GI cancer, or dietary indiscretion; but his increased drinking means that we do have to also consider that the GI signs are due to a secondary infection and/or side effect of organ issues (ie kidney, liver) or metabolic disease (ie thyroid issues, etc). So, we do need to tread with care.
Now given that this sounds to be taking a toll, it would be ideal to have him seen at this point. That way we can have bloods checked to rule out/confirm underlying disease, make sure he has no sinister lumps/bumps and have his vet start injectable anti-nausea medication +/- antibiotics to nip this in the bud.
Otherwise, in the meantime, we'd want to start supportive care for Smoke. To start, if he hasn’t just vomited (since otherwise we’d need to rest the stomach for a few hours first), you can consider treating with an OTC pet safe antacid [ie Pepcid (More Info/Dose @http://www.petplace.com/article/drug-library/library/over-the-counter/famotidine-pepcid), Tagamet (More Info/Dose Here @ http://www.petplace.com/article/drug-library/library/over-the-counter/cimetidine-hcl-tagamet)]. Whichever you choose, we’d give this 20 minutes before offering food to allow absorption. Of course, do double check with your vet if he has a known health issues or is on any medications you haven't mentioned. Also if you give this and he cannot keep it down due to nausea that is usually a red flag that we need to bypass his mouth with injectable anti-vomiting medication from his vet.
If we can soothe his stomach, we can follow this with an easily digestible diet like boiled chicken, boiled white fish, scrambled eggs, or meat baby food (garlic/onion free only) There are also OTC vet diets (ie Hill’s I/D or Royal Canin’s sensitivity) that can be used too. The aim of these diets is that they will be better tolerated/absorbed by the compromised gut. Therefore, it should get more nutrients in and result in less GI upset and less diarrhea. We can even add feline probiotics (ie Benebac, Fortiflora) and fiber (ie canned pumpkin or 0.25tsp Metamucil mixed into canned food) to firm the feces and support the gut and slow his losses via diarrhea.
Since dehydration is a risk even with his increased thirst, we need to keep an eye on his hydration. To check this and make sure dehydration isn’t an issue, there are a few parameters you can test. Further to checking for gum moisture, you will want to make sure his eyes are not looking sunken and that he doesn’t have a "skin tent" when you lift the skin. To see how to check these, you can find a good video HERE (http://www.ehow.com/video_12232503_dog-dehydrated.html). If you do see any of these signs already, then that would be our cue to have him seen before this becomes an additional issue (especially since its often dehydration that makes them feel unwell).
Finally, as long as there is no blood in those stools, you can consider trying a pet safe anti-diarrheal. As I am sure you appreciate, these would not be a cure for infectious issues; but it can still be of benefit. It will reduce diarrhea load, allow the body to absorb more water/nutrients, and soothe the upset gut. In regards ***** ***** options, the one we most commonly use is OTC Kaolin/Kaopectate (More Info/Dose @ http://www.petplace.com/article/drug-library/library/over-the-counter/kaolin-and-pectin-kapectolin-k-p)). Otherwise, Propectalin, Canikur, Fast Balance, and Protexin Pro-Fiber (which is available OTC at vets, pet stores, and even Amazon) would be another option. All will slow diarrhea and those last ones have the added bonus of providing support to the delicate good GI bacteria. So, these can be used as a short-term means of soothing his upset GI.
Overall, a wide range of agents could trigger the signs we are seeing with Smoke. Though his increased thirst and weight loss makes me worried that these GI signs are secondary to an underlying systemic/organ issue. Therefore, we’d want to start supportive care to try to settle his stomach. Though it would be ideal to plan a check up for him to get to the root issues too. His vet can assess his hydration, check bloods to make sure his organs are working as they should, ensure no masses are present in the gut, or any sinister viruses present. Depending on their findings, his vet can treat with injectable anti-vomiting medication +/- antibiotics and treatment for any of those underlying issues to this before he wastes away on us.
Please take care,
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