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Hello, this is Dr. Jess. I am so sorry to hear about Duke. Is this a boy cat?
Do you know if he has urinated today?
Oftentimes owners mistake a cat trying to have a bowel movement/being constipated, for a cat who is straining to urinate. Male cats can develop a life threatening condition called urethral obstruction where a blockage becomes present in the urethra (the tube that carries urine from the bladder to the outside via the penis) and they are unable to urinate. This is an emergency situation and can become life threatening. I would highly recommend getting your cat to an emergency vet right now unless you are absolutely certain that he is still urinating. This is not something that can wait until your vet reopens tomorrow if he has a urinary obstruction.
Here is an article describing this condition in cats: http://www.veterinarypartner.com/Content.plx?P=A&S=0&C=0&A=1111.
Once again, it is considered an emergency situation.
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