Hello, my name is***** and I have over 20 years of experience as a veterinarian. I understand your concern about Cuddles's behavior.
Is she spayed?
With the increasing daylight hours if she is not spayed it is very likely that she is going into, or is currently in, heat.
Typical behavior includes rolling, crouching with the rear in the air, especially in response to any sort of petting, increased vocalization, and increased scent marking.
She's not in pain, she's announcing to the boys she's available.
Cats will continuously cycle through heats unless bred or manually stimulated about every 2-3 weeks until late fall.
If she hasn't displayed this behavior before there are either males hanging around this time that she can smell or hear and is stimulated by, or some females get more vocal about their heats as they get older.
Either way if you don't want kittens it's time to spay her. Don't worry about waiting for her to come out of heat to spay her, that is impossible with cats because they constantly cycle, and their internal reproductive tract changes aren't as dramatic as dog's are, so we don't have to wait for them to come out of heat.
Can I answer anything else?