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My name is***** and I am sorry to hear that Pixi is so uncomfortable. Based on your history, it sounds like she is in pain. Cats are very good at hiding their pain and can be difficult to diagnose.
The most likely cause of pain would be arthritis. Arthritis is most commonly found in the elbows and the lower back. Other causes would include abdominal pain, especially from the pancreas or the bladder.I would recommend taking her to see your regular veterinarian. They will likely recommend blood work and a urinalysis and possibly a test for pancreatitis. They will also recommend x-rays of the spine and legs to see if there is arthritis.
Treatments are varied, depending on what they find. The best acute pain control is Buprenorphine, but this only lasts 6 to 8 hours. Long term treatments include an NSAID called Oncior, and nutritional management like glucosamine and fish oil.
Best regards, ***** ***** this answer helps you. Feel free to contact me if you have any more questions.
Kansas State University,
College of Veterinary Medicine Class of 2001
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