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Rebecca
Rebecca, Cat Veterinarian
Category: Cat Veterinary
Satisfied Customers: 13325
Experience:  More than 30 years of companion animal practice.
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Thankyou last answer. I did the quantative pcr and new elisa

Customer Question

thankyou for your last answer. I did the quantative pcr and new elisa test on both of my cats . Marmalade the * ( who I thinkis more 10 ) , his elisa came back negative - quantative pcr , was very low , confirming that the virus was latent/regressive not
active. my 3 year girl was negative in elisa and pcr so very happy . Marmalade bloods though do show iregaularites and I am still waiting to hear what they think it is so I would appreciate your opion as he is still loosing his appetite and loosing wieght.
He did have a felv vacination in march .... could this have started it off .... his wieght change etc.... I also have a resuce cat that is totally separated she is felv + with moderate to hight values of the virus , but first I would like to ask re: marmalade
and he is my priority . thank you rebecca.
Submitted: 1 year ago.
Category: Cat Veterinary
Expert:  Rebecca replied 1 year ago.

Good to hear from you again. I am glad to hear that Marmalade's Elisa was negative.

Have any other blood tests been done on him: chemistries to check liver and kidney function, blood sugar, electrolytes, etc.? He could have an illness unrelated to feline leukemia.

My understanding is that an IFA test is the best way to rule out that a cat is infected and sick because of the virus.

Customer: replied 1 year ago.
thank you rebecca , I have attahced the test we have done on him so you can see .
the elisa is the practically the same as the ifa , but also doing the quantative pcr showed that he had very low values of the virus - also is attached the results .
please have a look at his blood works , I have tried to understand them .
Expert:  Rebecca replied 1 year ago.

No, the ELISA is not at all the same as IFA. ELISA tests for the presence of virus in the blood viremia. Many cats will be transiently viremic, but never get infected. IFA tests for a marker that shows that the blood cells have been infected and transformed by the virus, and are now producing viral DNA. These cats are infected, and will sicken and eventually die.

Customer: replied 1 year ago.
I did the tests in bristol university hospital lab - Langford and they recomeneded
the QPCR - FELINE LEUCEMIA VIRUS
FELV AG ( elisa ) + FELV DNA PCR please have a look at the results , here you will see the amount of the proviral in his dna
Expert:  Rebecca replied 1 year ago.

Yes, I did look at the reports and saw the PCR tests and amount of proviral. That does not tell me why Marmalade is losing weight and not eating well. It could be related to feline leukemia infection, or it could be something else. I would need to see his "CBC and chemistry" results. It says in the first report that these are "to follow", so these tests were done. Do you have the results of those tests?

Customer: replied 1 year ago.
I attahced 4 files - 2 complete blood works plus a test for thyroid which is ok .
Customer: replied 1 year ago.
marmalade blood test
Customer: replied 1 year ago.
marmalade extended blood
Expert:  Rebecca replied 1 year ago.

OK now I see the white blood counts and they are low. This could be related to feline leukemia, another viral disease, or bone marrow disease. Further viral testing and possibly a bone marrow biopsy might tell us more about this. He is not anemic, his red cell counts are good.

There are a few blood chemistries, showing that his kidney function may be reduced (high urea, high phosphate). I would do a urinalysis to learn more about his kidney function.

Customer: replied 1 year ago.
Great you can see them now .... in NOCHE they are the same test so have a look at the numbers , her are much worse.
Marmalade is 10 so he is my priority , what can I do to help increase the white blood cells
Expert:  Rebecca replied 1 year ago.

The only way to increase the cells, is to find out why they are low. That might involve testing for other viruses, or even a bone marrow biopsy.

Customer: replied 1 year ago.
i wont do a bone marrow biopsy ... he was tested for fiv and he is negative . shall I give him a general convenia antibiotic ?
Expert:  Rebecca replied 1 year ago.

Antibiotics treat bacterial infections, not viral. Bacterial infections usually cause high white blood cell counts, not low. You could try the Convenia, but I am not sure it will help.

Customer: replied 1 year ago.
thank you , so viral cannot be treated in any way ....
Expert:  Rebecca replied 1 year ago.

There are a very few anti viral drugs, that are specific for particular viruses, but no broad spectrum anti viral drugs like we have antibiotics.

Expert:  Rebecca replied 1 year ago.
Hi Anna,
I'm just following up on our conversation about Marmalade. How is everything going?
Rebecca