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Dr. Kara
Dr. Kara, Veterinarian
Category: Cat Veterinary
Satisfied Customers: 14568
Experience:  Over 20 years of experience as a veterinarian.
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My 14 year old tonkinese eyes ( irises) have turned brown.

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My 14 year old tonkinese eyes ( irises) have turned brown. Aids, feline leukemia have been ruled out. Chemistry panel was essentially normal except for slightly elevated kidney values and elevated glucose (vet thought due to stress ) . I treated with eye drops (steroid ) which has not helped much. Now the mucosa is swollen accompanied by some weeping in the OD. He has his eyes closed a lot more now. Please advise.

Hello, my name isXXXXX and I have over 20 years of experience as a veterinarian.

I'm sorry to hear about Sammy's eyes and I am very concerned for him.


What you have described is a condition called uveitis, which is inflammation of the eye including the iris, blood vessels that supply nutrition to the eye and the muscles that control pupil size.

Symptoms of uveitis include squinting, sensitivity to light, raised third eyelids, tearing, redness to the white part of the eye, abnormal pupil shape or size, and a change in iris color. Some cats will also have cataract formation or cloudiness to the eye and if glaucoma develops secondarily a larger then normal, protruding eye.


There can be many reasons for uveitis but in the majority of cases (60%) we never find the cause. In cases where a cause can be identified though it is usually due to serious diseases including infectious diseases like feline leukemia, feline immunodeficiency virus, feline infectious peritonitis, toxoplasmosis, bartonella or Herpes virus, trauma or cancer including melanoma or lymphoma.


If a cat has uveitis for long enough and it is not successfully controlled it can progress to glaucoma, or increased intraocular pressure. That is what I am concerned about now with your fellow.


I would recommend starting by testing Sammy for feline leukemia, feline immunodeficiency virus (which have been done) and toxoplasmosis.

I also recommend checking his intraocular eye pressures and getting him examined by a veterinary ophthalmologist. If you'd like to find one in your area here is a link:

A veterinary ophthalmologist will be able to look inside his eyes to look for a tumor, check for glaucoma and examine his eyes much more closely because they have specialized equipment to do so.


In the meantime to control inflammation I would add an oral anti-inflammatory to the topicals he is already being given.


I cannot recommend more directed therapy without knowing why your fellow's eyes are the way that they are.

Best of luck with Sammy.

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Hi Cat Lover,

I'm just following up on our conversation about your pet. How is everything going?

Dr. Kara