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There is a few things that will cause this to happen
I would first look over the electrical closely
Has there been any work on the engine or transmission?
If so that is where to start.
then you can one at a time
test the a/c.02 sensor.ignition.fuel pump
To see witch is drawing high or a short in amperage
Many times it will be a loose ground or weak fuel pump that will blow the fuse.
Let me know if i can help more!