How JustAnswer Works:

  • Ask an Expert
    Experts are full of valuable knowledge and are ready to help with any question.
  • Get a Professional Answer
    Via email, text message, or notification as you wait on our site.
    Ask follow up questions if you need to.
  • 100% Satisfaction Guarantee
    Rate the answer you receive.

Ask FamilyPhysician Your Own Question

FamilyPhysician
FamilyPhysician, MD, MBA
Category: General
Satisfied Customers: 12655
Experience:  Primary care physician for transplant patients
1304720
Type Your Organ Transplantation Question Here...
FamilyPhysician is online now
A new question is answered every 9 seconds

My 33 year old son received my kidney (his mother) when he

Resolved Question:

My 33 year old son received my kidney (his mother) when he was 14 years old. Today he revealed to me that he has stopped taking his cyclosporine, the anti-rejection, immune suppressing drug. He said he has not taken it in 2 months! I am very frightened and made him promise that he would resume taking the drug. He says that there are a very few people whose antigens have such a close match that they do not have to take the drug. He was diagnosed with renal dysplasia when he was 4 years old. He had one non-working kidney removed at that time and then when he was 14 received my kidney. Is this true? How long does it take for rejection to begin? His creatinine has remained the same, about 1.3. He is not good about having regular blood work or seeing his nephrologist. He is married and is the father of a 1 year old with another on the way. He says he feels good.  Please advise.
Submitted: 2 years ago.
Category: Organ Transplantation
Expert:  FamilyPhysician replied 2 years ago.
Thank you for your question:

Non-compliance with immune suppressant medications (such as cyclosporine) is a major risk factor for rejection. This rejection could be acute (sudden) or chronic. In either case, his chance of keeping the kidney and remaining healthy without anti-rejection medications is very poor.

The fact that he has not had any sudden problems, does NOT mean that he will not have problems next week, next month or next year. In medicine, I try to avoid "always" and "never", but I can assure you that the risk if VERY high that he will loose this kidney, and end up on dialysis sooner or later.

He needs to discuss he concerns (side effects, costs, inconvenience etc) about this medication with his transplant nephrologist.

Here are some studies that look at the unfortunately common problem of non-compliance
http://www.ncbi.nlm.nih.gov/pubmed/11982618
http://www.ncbi.nlm.nih.gov/pubmed/20847093
http://www.ncbi.nlm.nih.gov/pubmed/20584734
http://www.ncbi.nlm.nih.gov/pubmed/21077956
FamilyPhysician, MD, MBA
Satisfied Customers: 12655
Experience: Primary care physician for transplant patients
FamilyPhysician and other Organ Transplantation Specialists are ready to help you
Customer: replied 2 years ago.
I would like you to respond to the information that he has about people who have very close antigens and don't seem to require the drugs. I'd like to know if that ever happens. What is the percentage. HOW LONG BEFORE REJECTION ON THE AVERAGE BEGINS WHEN MEDICINE IS NOT TAKEN?
Expert:  FamilyPhysician replied 2 years ago.
While it is "possible", it is not common and not something that should be attempted without close medical supervision.
http://abcnews.go.com/Health/post-transplant-regimen-eliminate-immunosuppressants/story?id=14673242#.T906nr8VyRA

http://www.nih.gov/news/health/may2010/niaid-25.htm

Making the assumption, that since he has not lost the kidney in 2 months, is a dangerous approach. This is something that really needs medical supervision, and he needs to be aware of the risks.

JustAnswer in the News:

 
 
 
Ask-a-doc Web sites: If you've got a quick question, you can try to get an answer from sites that say they have various specialists on hand to give quick answers... Justanswer.com.
JustAnswer.com...has seen a spike since October in legal questions from readers about layoffs, unemployment and severance.
Web sites like justanswer.com/legal
...leave nothing to chance.
Traffic on JustAnswer rose 14 percent...and had nearly 400,000 page views in 30 days...inquiries related to stress, high blood pressure, drinking and heart pain jumped 33 percent.
Tory Johnson, GMA Workplace Contributor, discusses work-from-home jobs, such as JustAnswer in which verified Experts answer people’s questions.
I will tell you that...the things you have to go through to be an Expert are quite rigorous.
 
 
 

What Customers are Saying:

 
 
 
  • Wonderful service, prompt, efficient, and accurate. Couldn't have asked for more. I cannot thank you enough for your help. Mary C. Freshfield, Liverpool, UK
< Last | Next >
  • Wonderful service, prompt, efficient, and accurate. Couldn't have asked for more. I cannot thank you enough for your help. Mary C. Freshfield, Liverpool, UK
  • This expert is wonderful. They truly know what they are talking about, and they actually care about you. They really helped put my nerves at ease. Thank you so much!!!! Alex Los Angeles, CA
  • Thank you for all your help. It is nice to know that this service is here for people like myself, who need answers fast and are not sure who to consult. GP Hesperia, CA
  • I couldn't be more satisfied! This is the site I will always come to when I need a second opinion. Justin Kernersville, NC
  • Just let me say that this encounter has been entirely professional and most helpful. I liked that I could ask additional questions and get answered in a very short turn around. Esther Woodstock, NY
  • Thank you so much for taking your time and knowledge to support my concerns. Not only did you answer my questions, you even took it a step further with replying with more pertinent information I needed to know. Robin Elkton, Maryland
  • He answered my question promptly and gave me accurate, detailed information. If all of your experts are half as good, you have a great thing going here. Diane Dallas, TX
 
 
 

Meet The Experts:

 
 
 
  • Ron

    ASE Certified Technician

    Satisfied Customers:

    21711
    23 years with Ford specializing in drivability and electrical and AC. Ford certs and ASE Certs
< Last | Next >
  • http://ww2.justanswer.com/uploads/FO/fordguy4u/2011-12-17_222940_HPIM1257.64x64.JPG Ron's Avatar

    Ron

    ASE Certified Technician

    Satisfied Customers:

    21711
    23 years with Ford specializing in drivability and electrical and AC. Ford certs and ASE Certs
  • http://ww2.justanswer.com/uploads/lyeung1/2010-07-25_032152_tn_IMG_0241.JPG Dr. Y.'s Avatar

    Dr. Y.

    Urologist

    Satisfied Customers:

    18704
    I am fellowship trained specializing in general urology and reconstructive urology.
  • http://ww2.justanswer.com/uploads/docjohn174/2008-12-13_170143_johnask.jpg John's Avatar

    John

    Home Appliance Technician

    Satisfied Customers:

    13453
    Appliance repair business owner for over 43 years.
  • http://ww2.justanswer.com/uploads/MU/multistatelaw/2011-11-27_173951_Tinaglamourshotworkglow102011.64x64.jpg Tina's Avatar

    Tina

    Lawyer

    Satisfied Customers:

    8658
    JD, BBA Over 25 years legal and business experience.
  • http://ww2.justanswer.com/uploads/dermdoc19/2010-09-30_160749_Photo_122807_015.JPG dermdoc19's Avatar

    dermdoc19

    Dermatologist

    Satisfied Customers:

    3937
    30 years practice in general and cosmetic dermatology
  • http://ww2.justanswer.com/uploads/BI/birddoctor/2012-6-22_173214_birddoctor.64x64.png Dr. Pat's Avatar

    Dr. Pat

    Bird Veterinarian

    Satisfied Customers:

    3457
    25+ years working primarily or exclusively with birds
  • http://ww2.justanswer.com/uploads/RY/rydergar/2012-6-6_192240_IMG0328.64x64.JPG Dr. Gary's Avatar

    Dr. Gary

    Cat Veterinarian

    Satisfied Customers:

    3390
    DVM, Emergency Veterinarian, BS (Physiology)
 
 
 
Chat Now With An Organ Transplantation-expert
FamilyPhysician
FamilyPhysician
Organ Transplantation-expert
12655 Satisfied Customers
Primary care physician for transplant patients